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Oxotremorine sesquifumarate

Oxotremorine sesquifumarate
Oxotremorine sesquifumarate is a muscarinic agonist.
Catalog No. T23116Cas No. 17360-35-9
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Purity:99.94%
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Oxotremorine sesquifumarate

Catalog No. T23116Cas No. 17360-35-9
Oxotremorine sesquifumarate is a muscarinic agonist.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$57In Stock
10 mg$93In Stock
25 mg$189In Stock
50 mg$278In Stock
100 mg$418In Stock
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Product Introduction

Bioactivity
Description
Oxotremorine sesquifumarate is a muscarinic agonist.
In vitro
Oxotremorine (10.5 micron) produced a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1].
In vivo
Rats with signs of neuropathy were subjected to SCS applied in awake, freely moving condition. Oxotremorine was administered intrathecally. Tactile, cold and heat sensitivities were assessed by using von Frey filaments, cold spray and focused radiant heat, respectively. Oxotremorine i.t. dose-dependently suppressed the tactile hypersensitivity. SCS markedly increased withdrawal thresholds (WTs), withdrawal latencies and cold scores[2].
Chemical Properties
Molecular Weight380.39
FormulaC12H18N2O·3/2C4H4O4
Cas No.17360-35-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (144.58 mM)
H2O: < 8 mg/mL (21.03 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.6289 mL13.1444 mL26.2888 mL131.4440 mL
5 mM0.5258 mL2.6289 mL5.2578 mL26.2888 mL
10 mM0.2629 mL1.3144 mL2.6289 mL13.1444 mL
20 mM0.1314 mL0.6572 mL1.3144 mL6.5722 mL
DMSO
1mg5mg10mg50mg
50 mM0.0526 mL0.2629 mL0.5258 mL2.6289 mL
100 mM0.0263 mL0.1314 mL0.2629 mL1.3144 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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